The Role of the Amino and Hydroxyl Groups of Collagen in Chrome
نویسنده
چکیده
1. Inmildlyalkaline suspension collagenis acetylated by acetic anhydride at the free amino groups. The number of N-acetyl groups introduced is equal to the total number of lysine and hydroxylysine residues found by analysis. 2. Dry collagen does not react with cold acetic anhydride, but in the presence of acetic acid or of small amounts of water both Nand O-acetylation take place. 3. The reaction is a slow one and is catalysed by acetic acid or, indirectly, bywater. At its completion all the E-amino groups and about 77 % of the hydroxyamino-acid residues of the protein have reacted.
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